"Experimental Chimeras' Removal of Reproductive Barrier Between Sheep and Goat" (1984), by Sabine Meinecke-Tillmann and Burkhard Meinecke
نویسندگان
چکیده
In 1984 Sabine Meinecke-Tillmann [5] and Burkhard Meinecke [6] published their article ?Experimental Chimeras ? Removal of Reproductive Barrier Between Sheep and Goat? in Nature. Their study conquered the reproductive barrier between sheep [7] and goats through embryo manipulation. Their article appeared in Nature on the same day that a similar experiment, conducted by Carole Fehilly [8], Steen Willadsen [9], and Elizabeth Tucker [10] was published regarding reproductive barriers between sheep [7] and goats. In previous experiments involving the transplantation of sheep [7] embryos into recipient goats or vice versa, the embryos did not survive past the initial weeks of pregnancy [11]. Hybridization experiments had also failed between the species. Although scientists were unsure of the reasons that hybrid eggs from donor sheep [7] did not survive, they attributed the death of the hybrid eggs from donor goats to immunological responses. Meinecke-Tillmann and Meinecke created interspecific chimeric embryos in order to address the reproductive obstacles between the species. These embryos were transferred to sheep [7], and a sheep [7] successfully brought a goat [12] kid to term.
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